Blood Group Systems: Name with Chromosomal Location
Number Name Symbol Number of Antigens Gene Names Chromosomal Location 001 ABO ABO 4 ABO 9q34.2 002 MNS MNS 43 GYPA, GYPB, GYPE 4q31.21 003 P P1 1 22q11.2-qter 22q11.2-qter…
miRNA Markers for Vaginal Secretions and MenstrualBlood Identification
Bodily Fluid miRNA Marker Full Sequence First 5 Sequences Vaginal Secretions miR124a UAAGGCACGCGGUGAAUGCC UAAGG Vaginal Secretions miR372 AAAGUGCUGCGACAUUUGAGCGU AAAGU Vaginal Secretions miR617 AGACUUCCCAUUUGAAGGUGGC AGACU Vaginal Secretions miR891a UGCAACGAACCUGAGCCACUGA UGCAA Menstrual…
TLC systems and visualization reagents for different drug compounds
Drug TLC Mobile Phase Visualization Reagent Result LSD Chloroform/methanol (9:1 v/v) 1. UV at 254 nm Absorbs 2. UV at 360 nm Fluorescence 3. Ehrlich’s reagent Blue/purple Opiates 1. Ethylacetate/methanol/ammonia…
Representative Markers of mRNA-Based Assays for Bodily Fluid Identification
Bodily Fluid Gene Symbol Description Blood ALAS2 Aminolevulinatesynthase 2 AMICA1 Adhesion molecule, interacts with CXADR antigen 1 ANK1 Ankyrin1 CD3G CD3 gamma molecule CD93 CD93 molecule HBA1 Alpha 1 hemoglobin…
Methods of Detecting DNA Methylation
Detecting DNA methylation can be done using several methods, each with its sequence of steps. Here is a generalized sequence incorporating various methods like Bisulfite Sequencing, Methylation-Sensitive Restriction Enzyme analysis…
Forensic Applications of Enzyme Reporting Systems for Detecting DNA
Reporter Enzyme Labeling Detection Method Mechanism Substrate Forensic Application AP AP-conjugated probe Chemiluminescent Lumigen® PPD RFLP; blot assay for DNA quantitation Horseradish Peroxidase (HRP) Biotinylated probe, recognized by streptavidin conjugated…
Three Basic DNA Extraction Methods
Method Forensic Application Purity DNA Strand DNA Size Throughput Note Additional Note Solvent-based RFLP- and PCR-based assay High Double stranded Large Time-consuming; difficult to adapt for automation Uses toxic solvent;…
Brain Receptors and Influenced Drugs
Receptor Drugs/ Substances Dopamine D-2 Antipsychotics, Parkinson’s drugs, some recreational drugs Nicotinic Nicotine, Alzheimer’s drugs, addiction treatments Cholinergic Alzheimer’s drugs, Myasthenia gravis drugs, Glaucoma drugs Serotonin 5HT Antidepressants (SSRIs), anti-anxiety…
Types of Fibres with Examples and Their Origin
1. Natural Fibres – Vegetable Fibres 1A: Seed Fibres Fiber Origin Cotton Seedpod of plants in the genus Gossypium Kapok Seed pods of the kapok tree Ceiba pentandra Coir Fibre…
SWGDRUG Categories
Category A: Specific Examinations Technique Description Infrared spectroscopy (IR) A technique that uses the absorption of infrared radiation to produce a chemical fingerprint of a substance; can be used in…